LMBRD1 and TCP11

Data Source:
BioGRID (two hybrid)

		LMBRD1	TCP11
Description		LMBR1 domain containing 1	t-complex 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Vacuolar Membrane Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Acrosomal Vesicle Integral Component Of Membrane Sperm Flagellum Sperm Midpiece
	Molecular Function	Protein Binding ABC-type Vitamin B12 Transporter Activity Cobalamin Binding
	Biological Process	Cobalamin Metabolic Process Cobalamin Transport Viral Process Protein Localization To Lysosome Protein Localization To Vacuole	Signal Transduction Multicellular Organism Development Spermatogenesis Protein Kinase A Signaling Cell Differentiation Regulation Of CAMP-mediated Signaling Regulation Of Sperm Capacitation
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Drugs
Diseases		Methylmalonic aciduria (MMA)
GWAS		Response to statin therapy ( 20339536) Sleep duration ( 25469926)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Height ( 28552196 18391951) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)
Interacting Genes		1 interacting genes: TCP11	13 interacting genes: AIMP2 APP FANCF GRAPL GSTZ1 IKBKG KRTAP13-3 LMBRD1 MAP2K1 MED28 NPFFR1 VAV2 ZNF688
Entrez ID		55788	6954
HPRD ID		12877	01749
Ensembl ID		ENSG00000168216	ENSG00000124678
Uniprot IDs		Q9NUN5	B7ZAT8 Q8WWU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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