TCP1 and CCT5

Data Source:
HPRD (in vitro)

		TCP1	CCT5
Description		t-complex 1	chaperonin containing TCP1 subunit 5
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GO Annotations	Cellular Component	Pericentriolar Material Heterochromatin Acrosomal Vesicle Zona Pellucida Receptor Complex Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome	Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding	MRNA 3'-UTR Binding Protein Binding ATP Binding G-protein Beta-subunit Binding Protein Folding Chaperone MRNA 5'-UTR Binding Beta-tubulin Binding Unfolded Protein Binding
	Biological Process	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Interleukin-12-mediated Signaling Pathway Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Regulation Of Macrophage Apoptotic Process	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Pain ( 22956598)
Interacting Genes		14 interacting genes: CBFA2T2 CCT5 CCT7 CDC20 DUX4 FANCA PDCL PTEN SH3BP4 SUMO2 TUBA4A TUBA8 VRK2 YWHAQ	20 interacting genes: ACTA1 ACTA2 ACTB CDC20 DUXAP9 ELP1 ERCC6 HDAC3 IMMT MCPH1 PDCL SUMO2 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1 ZNRD2
Entrez ID		6950	22948
HPRD ID		01748	06468
Ensembl ID		ENSG00000120438	ENSG00000150753
Uniprot IDs		E7EQR6 P17987	B4DDU6 B4DX08 B4DYC8 B7ZAR1 E7ENZ3 E9PCA1 P48643 V9HW37
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8	5UYX 5UYZ 6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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