TCEA1 and IWS1

Data Source:
HPRD (in vitro)

		TCEA1	IWS1
Description		transcription elongation factor A1	interacts with SUPT6H, CTD assembly factor 1
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Nucleolus	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio ( 26631737)	Cardiac troponin-I levels ( 31014085)
Interacting Genes		18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61	10 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1
Entrez ID		6917	55677
HPRD ID		03252	07639
Ensembl ID		ENSG00000187735	ENSG00000163166
Uniprot IDs		A0A384MTX4 B7Z4W0 P23193	Q96ST2
PDB IDs		1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L	6EMR
Enriched GO Terms of Interacting Partners?
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