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TBX6 and METTL27
Data Source:
BioGRID
(two hybrid)
TBX6
METTL27
Description
T-box transcription factor 6
methyltransferase like 27
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA Binding
Protein Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Methyltransferase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Mesoderm Formation
Cell Fate Specification
Heart Looping
Cardiac Chamber Development
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Mesoderm Development
Positive Regulation Of Cell Population Proliferation
Anatomical Structure Morphogenesis
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Neuron Maturation
Signal Transduction Involved In Regulation Of Gene Expression
Somite Rostral/caudal Axis Specification
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Body fat distribution (arm fat ratio) (
30664634
)
Brain morphology (MOSTest) (
32665545
)
Eosinophil counts (
32888494
27863252
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
High light scatter reticulocyte count (
32888494
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean platelet volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Menarche (age at onset) (
25231870
)
Multiple sclerosis (
31604244
)
Red blood cell count (
29403010
32888494
27863252
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
Sum eosinophil basophil counts (
27863252
)
Interacting Genes
39 interacting genes:
C10orf55
C19orf54
C1orf94
CRX
CYSRT1
DAZAP2
HSFY1
HSFY2
INTS11
KLHDC7B
KRTAP11-1
KRTAP13-1
KRTAP6-2
KRTAP6-3
MAGED1
MEOX2
METTL27
MGAT5B
PLA2G10
POU2AF1
POU6F2
PRMT1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMA3
RBPMS
TBX15
TBX19
TCP11L1
TENT5B
TLE5
TOX4
TSC1
USP54
YPEL3
ZNF34
29 interacting genes:
A1CF
ATXN1
ATXN1L
CCDC120
CSTF2
DOK6
EFHC1
ENKD1
FOXC2
GLYCTK
GPANK1
GRB2
HGS
KDM1A
LMO4
NOXA1
PITX1
PPP1R32
PRKAB2
PRMT6
PROP1
SNRPC
TBX6
TEKT3
TFG
TLX3
VPS37C
ZIC1
ZNF77
Entrez ID
6911
155368
HPRD ID
03888
15661
Ensembl ID
ENSG00000149922
ENSG00000165171
Uniprot IDs
O95947
Q8N6F8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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