TAPBP and COPG1

Data Source:
HPRD (in vivo)

		TAPBP	COPG1
Description		TAP binding protein	COPI coat complex subunit gamma 1
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle
	Molecular Function	Protein Binding ABC-type Peptide Antigen Transporter Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding TAP Complex Binding	Structural Molecule Activity Protein Binding
	Biological Process	MHC Class Ib Protein Complex Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Immune Response Regulation Of Gene Expression Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Establishment Of Golgi Localization Organelle Transport Along Microtubule
Pathways		ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			S-(Dimethylarsenic)Cysteine
Diseases		Bare lymphocyte syndrome (BLS) type1
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488)	Height ( 31562340) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 UBC	19 interacting genes: ARCN1 ARF1 CDC42 COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 H2AX PPBP PTGES3 RHOQ SACM1L SCYL1 SUMO2 TAPBP TMED10 WBP2
Entrez ID		6892	22820
HPRD ID		09061	09887
Ensembl ID		ENSG00000231925	ENSG00000181789
Uniprot IDs		A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 O15533	Q9Y678
PDB IDs		3F8U 6ENY	1R4X
Enriched GO Terms of Interacting Partners?
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