TACR3 and PALS2

Data Source:
BioGRID (two hybrid)

		TACR3	PALS2
Description		tachykinin receptor 3	protein associated with LIN7 2, MAGUK family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane Sperm Midpiece	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Tachykinin Receptor Activity Protein Binding	Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Aging Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Hyperosmotic Salinity Response Response To Morphine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility	Protein-containing Complex Assembly
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Osanetant Talnetant Pavinetant
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Chronotype ( 30696823) Heel bone mineral density ( 30598549) Height ( 31562340) Menarche (age at onset) ( 27182965 25231870) Rosacea symptom severity ( 29771307) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		4 interacting genes: GPRASP1 TAC1 TAC3 TAC4	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		6870	51678
HPRD ID		01209	09509
Ensembl ID		ENSG00000169836	ENSG00000105926
Uniprot IDs		P29371	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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