Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SYT5 and POLR2E
Data Source:
BioGRID
(two hybrid)
SYT5
POLR2E
Description
synaptotagmin 5
RNA polymerase II, I and III subunit E
Image
GO Annotations
Cellular Component
Plasma Membrane
Axon
Synaptic Vesicle Membrane
Dense Core Granule
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Recycling Endosome Membrane
Exocytic Vesicle
Integral Component Of Neuronal Dense Core Vesicle Membrane
Proximal Neuron Projection
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
RNA Polymerase III Complex
RNA Polymerase I Complex
Cytosol
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Calcium Ion Binding
Calcium-dependent Phospholipid Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Syntaxin Binding
Clathrin Binding
Protein Heterodimerization Activity
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Biological Process
Chemical Synaptic Transmission
Regulation Of Dopamine Secretion
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Synaptic Vesicle Endocytosis
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Cellular Response To Calcium Ion
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
Viral Process
RNA Metabolic Process
Positive Regulation Of Type I Interferon Production
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Regulation Of Gene Silencing By MiRNA
Pathways
Regulation of insulin secretion
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
Cytosolic sensors of pathogen-associated DNA
MicroRNA (miRNA) biogenesis
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
)
Cortical amyloid beta load (
29860282
)
Menopause (age at onset) (
26414677
)
Interacting Genes
6 interacting genes:
DNAJC5
HTR6
NRXN1
POLR2E
RAB1A
SYT3
29 interacting genes:
CHGB
FKBP14
FOS
GTF2B
GTF2F2
HSP90B1
IKBKG
IP6K3
ITCH
LZTR1
NEDD4
PML
POLR2A
POLR2C
POLR2D
POLR2F
POLR2G
POLR2H
POLR2K
POLR2L
SRPK1
SYT5
TAF15
TRIM29
TRIM55
TRIM63
UBE2D4
URI1
ZSCAN1
Entrez ID
6861
5434
HPRD ID
02870
15946
Ensembl ID
ENSG00000129990
ENSG00000099817
Uniprot IDs
A0A024R4N8
O00445
Q4FD32
B4DJ89
E5KT65
P19388
PDB IDs
5H4Y
5H4Z
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?