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SYT4 and SGTA
Data Source:
HPRD
(two hybrid)
SYT4
SGTA
Description
synaptotagmin 4
small glutamine rich tetratricopeptide repeat co-chaperone alpha
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Golgi Membrane
Integral Component Of Synaptic Vesicle Membrane
Axon
Dense Core Granule Membrane
Neuronal Cell Body
Neuron Projection Terminus
Synapse
Exocytic Vesicle
Astrocyte Projection
Intrinsic Component Of Neuronal Dense Core Vesicle Membrane
Neuronal Dense Core Vesicle
Nucleus
Cytoplasm
Cytosol
Membrane
TRC Complex
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Syntaxin-1 Binding
Clathrin Binding
Syntaxin-3 Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Protein Binding
Identical Protein Binding
Protein Self-association
Molecular Adaptor Activity
BAT3 Complex Binding
Biological Process
Vesicle Fusion
Brain Development
Regulation Of Dopamine Secretion
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Regulation Of Endocytosis
Cell Differentiation
Negative Regulation Of Vesicle Fusion
Negative Regulation Of Catecholamine Secretion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Positive Regulation Of Calcium Ion-dependent Exocytosis
Negative Regulation Of Neurotransmitter Secretion
Vesicle Fusion With Vesicle
Secretory Granule Maturation
Cellular Response To Calcium Ion
Dense Core Granule Cytoskeletal Transport
Positive Regulation Of Dendrite Extension
Negative Regulation Of Dense Core Granule Exocytosis
Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane
Viral Process
Ubiquitin-dependent ERAD Pathway
Tail-anchored Membrane Protein Insertion Into ER Membrane
Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Chaperone-mediated Protein Folding
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Accelerometer-based physical activity measurement (average acceleration) (
29899525
)
Body mass index (
28892062
25673413
)
Carotid intima media thickness x smoking interaction (
32117412
)
Ceramide levels (C24:0) (
32489964
)
Coffee consumption (
31046077
)
Metabolite levels (
23823483
)
Parkinson's disease (
28892059
21738487
)
Physical activity (moderate intensity activity duration) (
30531941
)
Physical activity (overall physical activity time) (
30531941
)
Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease (
29748315
)
Pulse pressure (
27841878
)
Pyoderma gangrenosum in inflammatory bowel disease (
24487271
)
Squamous cell lung carcinoma (
28604730
)
Systolic blood pressure (
27841878
)
Interacting Genes
12 interacting genes:
NBR1
NDUFA12
NRXN1
SGTA
SGTB
STX1A
STX2
STX3
STX4
SYNCRIP
SYT1
TFAP2B
176 interacting genes:
ADAM21
ADIPOQ
ADRM1
AGR2
AGR3
AOC3
BAG6
BCL2L12
BTC
C1QA
C1QL4
C1QTNF1
C1QTNF5
C1QTNF6
C3orf52
C5orf46
CD79B
CD99
CD99L2
CDH15
CDSN
CHRNG
COL1A2
COL8A2
CREB3L3
CSF1
CST1
CTAG1A
CTAG1B
CTSL
CXCL8
CYB5R1
DEFB131A
DKK3
DMKN
EDA2R
EDAR
EFEMP1
EFEMP2
ERP27
ERP29
ETNK1
EVA1B
F11R
FERD3L
FGF21
FIP1L1
FKBP7
FSTL1
FXYD2
FXYD7
FZD7
GABARAPL2
GAL
GALP
GHR
GIP
GPX7
GRN
GUCA2A
GYPA
HSP90AA1
HSP90AB1
HSPA13
HSPA4
HSPA8
IER3
IGFBP6
IGL
IGLC1
IL6ST
IRF3
IRF5
ITPRIPL1
KASH5
KCNA1
KCNA10
KCNE5
KRT6A
KTN1
LAIR2
LAT
LCN2
LDLRAD4
LSMEM2
MRAP2
MS4A3
MSMB
MSTN
MYDGF
MYOC
NAXD
NME3
NPVF
NR3C1
NRSN2
NXF1
PAGE3
PBXIP1
PCDHA4
PCDHGA4
PFN2
PGLYRP2
PGR
PIAS1
PLAAT4
PMEPA1
PPIB
PPIC
PPP1R3C
PRAP1
PRB4
PRRG2
PSORS1C2
PTN
PYY
RCN1
RNASE10
RNF144A
RNF144B
RNF170
RPN1
SDC4
SDF2L1
SERPINE1
SERPINI2
SGCA
SGTB
SHISA4
SHISA5
SLPI
SMAGP
SMIM14
SMIM5
SOD3
SPINK9
SPN
SPP1
SPPL2A
SRGN
SRL
STMP1
SUOX
SYT11
SYT4
TFF3
TFRC
TGFA
TMEM154
TMEM174
TMEM230
TMEM31
TMEM98
TMPO
TMPRSS11D
TMUB2
TNFRSF10C
TNFRSF13B
TNFRSF19
TNFRSF1A
TNFRSF21
TNFSF12
TRIM5
TWSG1
TXNDC12
UBL4A
UBQLN2
UPK3A
VIP
WBP1L
WFDC12
WFDC13
WFDC5
ZBTB8B
ZG16
ZG16B
Entrez ID
6860
6449
HPRD ID
02519
04568
Ensembl ID
ENSG00000132872
ENSG00000104969
Uniprot IDs
Q9H2B2
O43765
PDB IDs
1UGK
2VYI
4CPG
4GOD
4GOE
4GOF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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