MED22 and MED27

Data Source:
HPRD (in vitro)

		MED22	MED27
Description		mediator complex subunit 22	mediator complex subunit 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mediator Complex	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytosol Mediator Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Malaria ( 31844061)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Gout (normal type) ( 32238385) Triglyceride levels ( 32203549)
Interacting Genes		12 interacting genes: FBXO7 GOLM1 HGS MED11 MED17 MED27 MED30 MED8 MED9 NTAQ1 THOC7 TXNDC9	11 interacting genes: AFP ARFGAP1 ESR1 FBXO7 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5
Entrez ID		6837	9442
HPRD ID		01713	05438
Ensembl ID		ENSG00000148297	ENSG00000160563
Uniprot IDs		A0A024R8C5 Q15528	A0A024R8B7 Q6P2C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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