MED22 and MED17

Data Source:
HPRD (in vitro)

		MED22	MED17
Description		mediator complex subunit 22	mediator complex subunit 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mediator Complex	Nucleus Nucleoplasm Transcription Regulator Complex Membrane Mediator Complex Core Mediator Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Malaria ( 31844061)
Interacting Genes		12 interacting genes: FBXO7 GOLM1 HGS MED11 MED17 MED27 MED30 MED8 MED9 NTAQ1 THOC7 TXNDC9	16 interacting genes: BCL6 CTDP1 ESR1 ESR2 HEMGN HNF4A MED19 MED22 MED30 MED8 PPARGC1A SMARCA4 SREBF1 SUZ12 TP53 USP49
Entrez ID		6837	9440
HPRD ID		01713	04816
Ensembl ID		ENSG00000148297	ENSG00000042429
Uniprot IDs		A0A024R8C5 Q15528	Q9NVC6
PDB IDs
Enriched GO Terms of Interacting Partners?
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