SUOX and CYB5R2

Data Source:
BioGRID (two hybrid)

		SUOX	CYB5R2
Description		sulfite oxidase	cytochrome b5 reductase 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Nucleus Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding FAD Binding
	Biological Process	Sulfur Compound Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase	Bicarbonate Transport Sterol Biosynthetic Process
Pathways		Sulfide oxidation to sulfate	Erythrocytes take up carbon dioxide and release oxygen
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)	Blood pressure ( 23972371) Malaria ( 31844061) Metabolite levels ( 23823483)
Interacting Genes		77 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC	20 interacting genes: AGR2 CDC23 COIL FANCL FFAR2 GOLGA2 HGS MED20 MEOX2 NFKBID PSMC6 REL SUOX TRAF1 TRAF2 TRIM55 TRIM63 TRIP13 YPEL3 ZNF778
Entrez ID		6821	51700
HPRD ID		06055	06435
Ensembl ID		ENSG00000139531	ENSG00000166394
Uniprot IDs		A0A024RB79 P51687	A8K237 Q6BCY4
PDB IDs		1MJ4
Enriched GO Terms of Interacting Partners?
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