ZFP36L1 and PAFAH1B2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZFP36L1	PAFAH1B2
Description		ZFP36 ring finger protein like 1	platelet activating factor acetylhydrolase 1b catalytic subunit 2
Image
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Metal Ion Binding 14-3-3 Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	MAPK Cascade Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Vasculogenesis Proepicardium Development MRNA Processing Apoptotic Process Heart Development Cell Population Proliferation Response To Wounding Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Phosphatidylinositol 3-kinase Signaling Neural Tube Development Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay Regulation Of MRNA 3'-end Processing Cellular Response To Insulin Stimulus T Cell Differentiation In Thymus Multicellular Organism Growth P38MAPK Cascade Regulation Of MRNA Stability Protein Kinase B Signaling Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Regulation Of Keratinocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Monocyte Differentiation Regulation Of Myoblast Differentiation Mesendoderm Development MRNA Transport Chorio-allantoic Fusion 3'-UTR-mediated MRNA Destabilization ERK1 And ERK2 Cascade Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Hypoxia Cellular Response To Salt Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Stem Cell Proliferation Cellular Response To Raffinose Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intracellular MRNA Localization	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation
Pathways		Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 31959851) Blond vs. brown/black hair color ( 30531825) Celiac disease ( 22057235 20190752 25920553) Crohn's disease ( 21102463) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Fibrinogen levels ( 28107422 26561523) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Microalbuminuria ( 31511532) Multiple sclerosis ( 24076602 21833088) Nonsyndromic cleft lip ( 31609978) Prostate cancer ( 23535732) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		9 interacting genes: ACD AKT1 MAPK14 MAPKAPK2 PAFAH1B2 POT1 TERF1 TINF2 YWHAB	19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1
Entrez ID		677	5049
HPRD ID		03041	03940
Ensembl ID		ENSG00000185650	ENSG00000168092
Uniprot IDs		A0A024R658 B3KNA8 Q07352	P68402 V9HW44
PDB IDs		1W0V 1W0W	1VYH
Enriched GO Terms of Interacting Partners?
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