PAFAH1B2 and RPLP0

Data Source:
HPRD (two hybrid)

		PAFAH1B2	RPLP0
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 2	ribosomal protein lateral stalk subunit P0
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GO Annotations	Cellular Component	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Dendrite Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Postsynapse Ribonucleoprotein Complex
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Interleukin-12-mediated Signaling Pathway Cellular Response To Interleukin-4
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)	Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1	12 interacting genes: CCNDBP1 CSNK2A1 ERG GAS7 KRI1 PAFAH1B2 PPM1A PRPF40A PTEN SMAD3 STAU1 YWHAQ
Entrez ID		5049	6175
HPRD ID		03940	01610
Ensembl ID		ENSG00000168092	ENSG00000089157
Uniprot IDs		P68402 V9HW44	A0A024RBS2 P05388
PDB IDs		1VYH	4V6W 4V6X 5AJ0 6OLG 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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