ST14 and NFRKB

Data Source:
BioGRID (affinity chromatography technology)

		ST14	NFRKB
Description		ST14 transmembrane serine protease matriptase	nuclear factor related to kappaB binding protein
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane	Nucleus Nucleoplasm Ino80 Complex
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Protease Binding DNA Binding Protein Binding
	Biological Process	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching Cornification	DNA Repair DNA Recombination Protein Deubiquitination
Pathways		Formation of the cornified envelope Formation of the cornified envelope	UCH proteinases DNA Damage Recognition in GG-NER
Drugs		Urokinase Benzamidine Camostat
Diseases		Ichthyosis with hypotrichosis
GWAS		Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)	High light scatter reticulocyte count ( 32888494) Night sleep phenotypes ( 27126917) Reticulocyte count ( 32888494)
Interacting Genes		17 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1	4 interacting genes: EPHB3 NFKB1 TRDMT1 UCHL5
Entrez ID		6768	4798
HPRD ID		06005	01240
Ensembl ID		ENSG00000149418	ENSG00000170322
Uniprot IDs		Q9Y5Y6	A0A024R3K9 Q6P4R8
PDB IDs		1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T	3U21 4UF5 4UF6 4WLP
Enriched GO Terms of Interacting Partners?
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