SSTR4 and CORT

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		SSTR4	CORT
Description		somatostatin receptor 4	cortistatin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Region Extracellular Space Fanconi Anaemia Nuclear Complex Synapse FANCM-MHF Complex
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding	G Protein-coupled Receptor Binding Chromatin Binding Neuropeptide Hormone Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Cell Migration Forebrain Development Somatostatin Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Glucocorticoid Stimulus Positive Regulation Of Arachidonic Acid Secretion Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Resolution Of Meiotic Recombination Intermediates G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Replication Fork Processing
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Somatostatin Lutetium Lu 177 dotatate
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood sugar levels ( 29403010) Hypothyroidism ( 27182965) Mitochondrial DNA copy number ( 30704525) Obesity-related traits ( 23251661) Vitamin D levels ( 26704534)	Male-pattern baldness ( 28196072)
Interacting Genes		2 interacting genes: CORT SST	7 interacting genes: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6754	1325
HPRD ID		01676	04150
Ensembl ID		ENSG00000132671	ENSG00000241563
Uniprot IDs		P31391	O00230 Q8IUV6
PDB IDs
Enriched GO Terms of Interacting Partners?
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