Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SRI and SHBG
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SRI
SHBG
Description
sorcin
sex hormone binding globulin
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Cytosol
Membrane
Sarcoplasmic Reticulum
Z Disc
T-tubule
Sarcoplasmic Reticulum Membrane
Chromaffin Granule Membrane
Axon Terminus
Dendritic Spine Neck
Extracellular Exosome
Extracellular Region
Extracellular Exosome
Molecular Function
Protease Binding
Signaling Receptor Binding
Calcium Channel Regulator Activity
Calcium Ion Binding
Protein Binding
Ion Channel Binding
Protein Heterodimerization Activity
Repressing Transcription Factor Binding
Steroid Binding
Androgen Binding
Protein Binding
Biological Process
Action Potential
Calcium Ion Transport
Intracellular Sequestering Of Iron Ion
Regulation Of Striated Muscle Contraction
Signal Transduction
Heart Development
Muscle Organ Development
Regulation Of Heart Contraction
Negative Regulation Of Heart Rate
Regulation Of Cell Communication By Electrical Coupling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Cytoplasmic Sequestering Of Transcription Factor
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Calcium Ion Transport
Negative Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Regulation Of Relaxation Of Muscle
Regulation Of High Voltage-gated Calcium Channel Activity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways
Stimuli-sensing channels
Reduction of cytosolic Ca++ levels
Sodium/Calcium exchangers
Ion homeostasis
Ion transport by P-type ATPases
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Masoprocol
Diethylstilbestrol
Levonorgestrel
Progesterone
Spironolactone
Toremifene
Estrone
Tamoxifen
Clomifene
Dienestrol
Hesperetin
Zinc
Genistein
Naringenin
Quercetin
4'-Hydroxyflavanone
Afimoxifene
Estriol
Phenolphthalein
Norethynodrel
Dioxybenzone
Zeranol
Gestrinone
Equol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Estriol tripropionate
Diseases
GWAS
Androgen levels (
22936694
)
Body size at age 10 (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Heel bone mineral density (
30598549
)
Hormone measurements (
24049095
)
Medication use (calcium channel blockers) (
31015401
)
Protein quantitative trait loci (
18464913
)
Red cell distribution width (
27863252
)
Refractive error (
32231278
)
Sex hormone levels (
26014426
)
Sex hormone-binding globulin levels (
22675492
22829776
)
Testosterone levels (
21998597
)
Uterine fibroids (
31649266
)
Interacting Genes
20 interacting genes:
ALG2
ANXA11
ANXA7
CACNA1C
CACNA1S
CALCOCO2
GCA
MTNR1A
NRAS
PDE4C
PRR13
PSEN2
RYR2
SHBG
SMAD2
SNCA
SRPK2
STAT3
TCF12
USHBP1
62 interacting genes:
A2M
ACP3
ACTA2
ACTB
ACTG2
AK2
AKR1B1
AP1B1
AP2A1
APEH
APOBEC3C
APOD
ASB16-AS1
ATP5F1A
AZGP1
C9orf24
CD177
CEP192
CLDN4
CLEC4G
COL1A2
CTSD
DDX3Y
DES
DSTN
EEF1A1
EIF3E
EIF3F
FLNA
FLOT1
FYTTD1
GRB2
HDHD5
HYI
JMJD7-PLA2G4B
KLK4
MPDU1
MT1F
MT1G
MT2A
MXD4
NOMO1
PACSIN2
PKM
PLA2G4A
PLP2
PSTPIP1
PSTPIP2
PTGDS
RMND5B
SEMA3F
SLC37A1
SLC37A4
SNAPIN
SNRNP70
SORD
SRF
SRI
TINAGL1
UBE2O
UBE3A
ZC3H12A
Entrez ID
6717
6462
HPRD ID
01680
01646
Ensembl ID
ENSG00000075142
ENSG00000129214
Uniprot IDs
B4DHQ6
C9J0K6
P30626
B0FWH2
B0FWH8
B4DYU0
I3L145
P04278
PDB IDs
1JUO
2JC2
4U8D
4UPG
4USL
5MRA
1D2S
1F5F
1KDK
1KDM
1LHN
1LHO
1LHU
1LHV
1LHW
6PYA
6PYB
6PYF
6ULB
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?