SHBG and AZGP1

Data Source:
BioGRID (two hybrid)

		SHBG	AZGP1
Description		sex hormone binding globulin	alpha-2-glycoprotein 1, zinc-binding
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome	Extracellular Region Extracellular Space Nucleus External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Steroid Binding Androgen Binding Protein Binding	Ribonuclease Activity Protein Binding Protein Transmembrane Transporter Activity
	Biological Process		Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Cell Adhesion Negative Regulation Of Cell Population Proliferation Transmembrane Transport Protein Transmembrane Transport RNA Phosphodiester Bond Hydrolysis
Pathways			Miscellaneous transport and binding events
Drugs		Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate	N-acetyl-alpha-neuraminic acid Copper
Diseases
GWAS		Androgen levels ( 22936694) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Refractive error ( 32231278) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266)	Brain morphology (MOSTest) ( 32665545) Red blood cell count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 C9orf24 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	5 interacting genes: ABCC1 ITGAV NUF2 SHBG UBQLN2
Entrez ID		6462	563
HPRD ID		01646	01910
Ensembl ID		ENSG00000129214	ENSG00000160862
Uniprot IDs		B0FWH2 B0FWH8 B4DYU0 I3L145 P04278	A0A140VK00 P25311
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB	1T7V 1T7W 1T7X 1T7Y 1T7Z 1T80 1ZAG 3ES6 6R2U
Enriched GO Terms of Interacting Partners?
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