SPRR1B and CRYBA1

Data Source:
BioGRID (affinity chromatography technology)

		SPRR1B	CRYBA1
Description		small proline rich protein 1B	crystallin beta A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Structural Molecule Activity	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Cornification	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Inflammatory skin disease ( 25574825)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes			24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3
Entrez ID		6699	1411
HPRD ID		01648	00429
Ensembl ID		ENSG00000169469	ENSG00000108255
Uniprot IDs		P22528	P05813
PDB IDs
Enriched GO Terms of Interacting Partners?
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