Description |
Spi-1 proto-oncogene |
DNA methyltransferase 3 alpha |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Body mass index ( 26426971)
- Body mass index (age <50) ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Body size at age 10 ( 32376654)
- Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
- Crohn's disease ( 28067908 21102463)
- Heel bone mineral density ( 30598549)
- Height ( 28552196 25282103 25429064 31562340 18391951)
- High light scatter reticulocyte count ( 32888494)
- High light scatter reticulocyte percentage of red cells ( 32888494)
- Inflammatory bowel disease ( 28067908)
- Lymphocyte counts ( 32888494 27863252)
- Lymphocyte percentage of white cells ( 32888494 27863252)
- Macular thickness ( 30535121)
- Monocyte count ( 32888494)
- Multiple sclerosis ( 31604244)
- Neutrophil percentage of white cells ( 32888494 27863252)
- Resistant hypertension ( 31545351)
- Type 1 diabetes ( 21980299)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for BMI in smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
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Interacting Genes |
45 interacting genes:
ATF1
BCL6
CEBPA
CEBPB
CEBPD
CEBPE
CREBBP
CREM
CSNK2A1
DNMT3A
DNMT3B
ERG
ETS1
ETS2
ETV1
FOS
FUS
GATA1
GATA2
GATA3
GFI1
HDAC1
HOXA10
IRF1
IRF2
IRF4
IRF8
JUN
KAT6A
MAPK8
MECP2
MITF
NFATC1
NFKB1
NFYA
NONO
PIP
RB1
RUNX1
SIN3A
SKI
SPIB
SSRP1
TBP
TMX1
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33 interacting genes:
CBX1
DDB1
DNMT1
DNMT3B
DNMT3L
EED
EHMT1
EHMT2
EZH2
F8A1
H3C1
H3C6
HDAC1
MDFI
MEOX2
MYC
NRIP1
PIAS1
PIAS2
PRMT5
PTGES3
SETDB1
SP100
SPI1
SUV39H1
TCL1A
TERF2IP
UBE2I
UHRF1
USP7
ZBTB17
ZBTB18
ZNF513
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Entrez ID |
6688 |
1788 |
HPRD ID |
01305 |
04141 |
Ensembl ID |
ENSG00000066336
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ENSG00000119772
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Uniprot IDs |
P17947
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A0A0C4DG02
F8WE91
Q59HC6
Q9Y6K1
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PDB IDs |
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2QRV
3A1A
3A1B
3LLR
3SVM
4QBQ
4QBR
4QBS
4U7P
4U7T
5YX2
6BRR
6F57
6PA7
6W89
6W8B
6W8D
6W8J
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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