UAP1 and RGS4

Data Source:
BioGRID (affinity chromatography technology)

		UAP1	RGS4
Description		UDP-N-acetylglucosamine pyrophosphorylase 1	regulator of G protein signaling 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	UDP-N-acetylglucosamine Diphosphorylase Activity Carbohydrate Binding Identical Protein Binding UDP-N-acetylgalactosamine Diphosphorylase Activity	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding
	Biological Process	UDP-N-acetylglucosamine Biosynthetic Process	Inactivation Of MAPK Activity Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Heart Rate Response To Cocaine Response To Morphine Positive Regulation Of GTPase Activity Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Actin Filament Organization Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Potassium Ion Transmembrane Transport Dorsal Root Ganglion Development Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Synthesis of UDP-N-acetyl-glucosamine	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs		Uridine-Diphosphate-N-Acetylgalactosamine Uridine-Diphosphate-N-Acetylglucosamine
Diseases
GWAS			Response to fenofibrate (triglyceride levels) ( 27002377) Response to mTOR inhibitor (rapamycin) ( 24009623)
Interacting Genes		1 interacting genes: FBXL17	13 interacting genes: CALM1 COPB1 COPB2 EGFR ERBB3 GABBR1 GNAI1 GNAI2 GNAO1 GNAQ KRIT1 PLCB1 PTAFR
Entrez ID		6675	5999
HPRD ID		04178	03947
Ensembl ID		ENSG00000117143	ENSG00000117152
Uniprot IDs		A0A140VKC0 Q16222	A0A024R909 P49798
PDB IDs		1JV1 1JV3 1JVD 1JVG
Enriched GO Terms of Interacting Partners?
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