SNTB1 and ADRA1D

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		SNTB1	ADRA1D
Description		syntrophin beta 1	adrenoceptor alpha 1D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Cytoskeleton Focal Adhesion Dystrophin-associated Glycoprotein Complex Protein-containing Complex Sarcolemma Synapse	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding PDZ Domain Binding	G Protein-coupled Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Muscle Contraction	Positive Regulation Of Heart Rate By Epinephrine-norepinephrine G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Positive Regulation Of MAPK Cascade Positive Regulation Of Vasoconstriction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Neuron-glial Cell Signaling
Pathways			Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs			Amphetamine Midodrine Ranolazine Cabergoline Ropinirole Dapiprazole Amitriptyline Alfuzosin Norepinephrine Mirtazapine Phenylephrine Prochlorperazine Prazosin Prazosin Imipramine Chlorpromazine Buspirone Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Phentolamine Ergotamine Tizanidine Tamsulosin Paroxetine Methoxamine Fenoldopam Dobutamine Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Promethazine Carvedilol Carvedilol Doxepin Desipramine Terazosin Escitalopram Pergolide Bromocriptine Quetiapine Mephentermine Methotrimeprazine Dextroamphetamine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Pizotifen Silodosin Ocaperidone Droxidopa Xylometazoline Perospirone Dosulepin Etoperidone Lorpiprazole Cirazoline Synephrine Arotinolol Moxisylyte Aranidipine Pipamperone Racepinephrine Dihydroergocornine DL-Methylephedrine Indigotindisulfonic acid Tiapride Dihydroergocristine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Cerebrospinal T-tau levels ( 28247064) Eye morphology ( 29921221) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29083408) JT interval (sulfonylurea treatment interaction) ( 27958378) Myopia (pathological) ( 23406873) Myopia (severe) ( 23933737) Periodontitis (CDC/AAP) ( 24024966) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thalamus volume ( 31530798)	Paneth cell defects in Crohn's disease ( 28352666) Preeclampsia ( 23551011) Sense of smell ( 26632684)
Interacting Genes		12 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA KCNJ12 MAPK12 RPS6KA1 SCN4A SCN5A UTRN	8 interacting genes: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1
Entrez ID		6641	146
HPRD ID		02490	00079
Ensembl ID		ENSG00000172164	ENSG00000171873
Uniprot IDs		Q13884	B0ZBE0 P25100
PDB IDs
Enriched GO Terms of Interacting Partners?
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