SNRPN and FBL

Data Source:
HPRD (in vitro)

		SNRPN	FBL
Description		small nuclear ribonucleoprotein polypeptide N	fibrillarin
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP Cytoplasm Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome Catalytic Step 2 Spliceosome	Fibrillar Center Dense Fibrillar Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D RNP Complex Small-subunit Processome Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Response To Hormone	Box C/D RNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation
Pathways		mRNA Splicing - Major Pathway	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Aspartate aminotransferase levels ( 31219225) Carotid plaque burden ( 28282560) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Obesity-related traits ( 23251661) Panic disorder ( 31712720) Periodontal disease related phenotype (PCT5) ( 26962152) Periodontitis (DPAL) ( 24024966) Pulmonary function ( 17903307)
Interacting Genes		11 interacting genes: ARL4D CTBP1 FBL GEMIN2 GTF2I KEAP1 LRIF1 MAFG RBFOX1 SH3GL3 TP53	22 interacting genes: DDX17 DDX5 ERG H2AC20 KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PRMT8 PSMB6 PTEN RUVBL1 RUVBL2 SIRT7 SMN1 SMN2 SNRPN TAF9 TBC1D17 ZNF792
Entrez ID		6638	2091
HPRD ID		01653	00617
Ensembl ID		ENSG00000128739	ENSG00000105202
Uniprot IDs		P63162 X5DP00	P22087
PDB IDs		5MF9	2IPX
Enriched GO Terms of Interacting Partners?
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