Description |
small ubiquitin like modifier 2 |
heat shock protein 90 alpha family class A member 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Rifabutin
- Nedocromil
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
- Geldanamycin
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
- 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine
- 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
- 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
- 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- Quercetin
- 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- Tanespimycin
- SNX-5422
- N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
- 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
- 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
- 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
- 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
- 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
- N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
- 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
- CCT-018159
- 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol
- 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
- 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
- (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime
- 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
- 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
- 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol
- 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide
- 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
- 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
- 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
- Copper
- Polaprezinc
- Alvespimycin
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Diseases |
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GWAS |
- Deep white matter hyperintensities ( 32517579)
- Gamma glutamyl transferase levels ( 29403010)
- Type 2 diabetes ( 32499647)
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- Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
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Interacting Genes |
454 interacting genes:
AARS1
ABCF1
ABRAXAS1
ACIN1
ACTB
AHCYL1
AHNAK
AHNAK2
AIMP1
ALAS1
ANAPC1
ANAPC2
ANLN
ANXA1
APRT
ARF3
ARF4
ARID2
ASNS
ASS1
ATF7IP
ATRX
ATXN7
BABAM2
BAD
BAZ1A
BAZ1B
BLM
BOD1L1
BPTF
BRCC3
BZW1
C18orf25
CAD
CALM1
CARS1
CAST
CCAR2
CCNE2
CCT2
CCT3
CCT4
CCT5
CCT6A
CDK2
CENPC
CHAF1A
CHAF1B
CHAMP1
CHD3
CHD4
CHD8
CKAP5
CLTC
CMTM6
COPA
COPB2
COPG1
CPSF2
CPSF7
CSE1L
CSNK2B
CTNNBL1
CTNND1
CTR9
CUL3
CUX1
DAB2
DARS1
DAXX
DCD
DDX1
DDX17
DDX21
DDX39A
DDX39B
DDX3X
DDX5
DIDO1
DIP2B
DNAJA1
DNM1L
DNMT1
DYNC1H1
EDC4
EEF1A1
EEF1A2
EEF1G
EEF2
EFTUD2
EGLN3
EHD4
EHMT1
EIF4A1
EIF4A2
EIF4G1
EIF4G2
EIF5A
ELAC2
EME1
EMG1
EML3
ENO1
EP300
EP400
EPPK1
EPRS1
ERCC4
ERCC6
EXOSC10
EXOSC9
EZR
FARSB
FASN
FBXO38
FLNA
FLNB
FOS
GALK1
GAPVD1
GATAD2B
GCN1
GEMIN5
GPATCH8
GTF2I
GTF3C1
GTF3C2
GTF3C4
GYS1
HCFC1
HDAC1
HDAC2
HDAC4
HDAC9
HDLBP
HIPK2
HK2
HMGXB4
HNRNPA0
HNRNPA1L2
HNRNPA2B1
HNRNPF
HNRNPH1
HNRNPH2
HNRNPK
HNRNPL
HNRNPLL
HNRNPM
HNRNPR
HNRNPU
HOMEZ
HP1BP3
HPS6
HSF2
HSP90AA1
HSP90AB1
HSPA1A
HSPA5
HSPA8
HSPA9
HSPB1
HSPD1
HUWE1
IARS1
ILK
IMPDH2
INTS3
IPO5
IQGAP1
JUN
KALRN
KARS1
KDM1A
KDM5C
KIF11
KIF18B
KIF23
KIF2A
KIF2C
KIF4A
KIF5B
KPNA2
KRT8
LARS1
LAS1L
LEF1
LMNA
LMO7
MAF1
MAP4
MARS1
MAST2
MCM3
MCM4
MDC1
MDN1
MKI67
MMS19
MORC3
MPI
MRE11
MSH2
MSH3
MSH6
MSX1
MTA1
MTA2
MTHFD1
MUS81
MYB
MYG1
NAP1L1
NARS1
NAT10
NBN
NCAPD2
NCAPD3
NCAPG
NCAPH2
NCL
NCOR1
NFATC2IP
NFE2L2
NIBAN2
NIPBL
NOL9
NONO
NOP2
NPM1
NSUN2
NUMA1
NUP107
NUP160
NUP214
ORC3
P4HA1
P4HB
PAF1
PALLD
PARN
PARP1
PBRM1
PDCD4
PDCD6IP
PDS5A
PELP1
PFKL
PFKM
PFKP
PGK1
PHF3
PHF5A
PHF8
PIAS1
PIAS2
PIAS3
PIAS4
PKM
PKN2
PLEC
PML
POGZ
POLA1
POLD1
POLR2A
PPP1CC
PPP2R1A
PRC1
PRDX6
PRKDC
PRPF6
PRPF8
PSMC1
PSMC3
PSMC4
PSMC5
PTBP1
RAD21
RAD50
RAD51
RAD54L2
RAN
RANBP2
RANGAP1
RARS1
RBBP4
RBBP7
RCC1
RCOR1
RCOR2
RCOR3
RFC2
RFC4
RFC5
RIF1
RNF111
RNF168
RNF20
RNF213
RNF216
RNF4
RNF8
RPL10
RPL3
RPL4
RPS3
RPS4X
RPS6KA3
RREB1
RRM1
RUVBL1
S100A10
SAE1
SAFB
SAFB2
SAMHD1
SARS1
SART1
SCAF11
SENP1
SENP2
SENP3
SENP5
SENP6
SENP7
SERPINB6
SETDB1
SETX
SF3A1
SF3B1
SF3B2
SIMC1
SIN3A
SIRT1
SLC22A2
SLX4IP
SMARCA4
SMARCAD1
SMC1A
SMC2
SMC3
SMC4
SMCHD1
SND1
SNRNP200
SNW1
SNX27
SOBP
SOX10
SOX6
SP1
SP100
SPATA5
SPATA5L1
SPR
SPTAN1
SPTBN1
SRCAP
SRP68
SRRM2
SRRT
SSRP1
STAG2
STIP1
STRAP
SUPT16H
SUPT5H
SYMPK
SYNCRIP
TAF1
TAGLN2
TCERG1
TCP1
TDG
TDP2
TEAD3
TEX10
TK1
TLN1
TMPO
TNIP1
TOP2A
TOP2B
TOPORS
TP53BP1
TP53BP2
TPR
TPX2
TRAF1
TRIM25
TRIM26
TRIM28
TRIM63
TRIML2
TRIP13
TRMT1L
TSR1
TTI1
TTLL12
TUBA1B
TUBA1C
TUBA4A
TUBB
TUBB4A
TUBB4B
TUBB6
U2AF2
UBA1
UBA2
UBAP2L
UBE2I
UBR4
UIMC1
UMPS
UPF1
USP11
USP25
USP28
USP48
USP5
USP7
USP9X
USPL1
VARS1
VIM
WAPL
WASHC2C
WDHD1
WRN
XAB2
XPNPEP1
XPO1
XPO5
XRCC5
XRCC6
YWHAQ
ZBED1
ZBTB2
ZBTB25
ZBTB33
ZBTB39
ZC3H11A
ZCCHC12
ZCCHC7
ZHX1
ZMAT3
ZMYM2
ZMYM3
ZMYM4
ZMYM5
ZMYND8
ZNF451
ZNF496
ZNF638
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158 interacting genes:
AHR
AHSA1
AHSA2P
AIP
AIPL1
AKT1
AKT2
APAF1
APOB
AR
ARNTL
ASGR1
BIRC5
BRMS1
CACYBP
CALM1
CDC37
CDC37L1
CDK4
CDK5R1
CDKN2A
CERS2
CFTR
CHEK1
CHORDC1
CHUK
CKS1B
CKS2
CRNKL1
CSNK2A1
CSNK2A2
DAP3
DNAJC7
EGFR
EGLN1
EIF2AK1
EIF2AK2
EIF2AK3
EIF2S1
EPAS1
EPRS1
ERBB2
ERN1
ESR1
ESRRB
FAM162A
FANCA
FANCC
FKBP1A
FKBP4
FKBP5
FKBP6
FLCN
FNIP1
FYN
GABARAPL1
GNA12
GSK3B
GUCY1B1
GZMA
HDAC6
HIF1A
HIF3A
HSF1
HSPA8
HTT
IKBKB
IKBKE
IKBKG
IP6K2
IRAK1
IRF3
ITGB1BP2
JUN
KDR
KEAP1
LCK
LINC01554
LSM1
MAP3K14
MAP3K3
MAPK1
MAPT
MIS12
MMP2
MS4A2
MTRNR2L1
MUC1
MYC
MYOD1
NDRG1
NOS1
NOS3
NPAS2
NR2C2
NR3C1
NR3C2
NSL1
PABPN1
PAK1
PDPK1
PIM1
PMF1
PPARA
PPARD
PPID
PPIL2
PPP5C
PRKACA
PRKCA
PRKCD
PRKDC
PTGDS
PTGES3
PTPRF
RAD51
RAF1
RHOBTB2
RIPK1
RPAP3
RPS3
RPS3A
RUNX1T1
SERPINB5
SGTA
SIM1
SKP1
SLC2A4
SLC34A1
SMYD2
SMYD3
SNCA
SRC
ST13
STARD13
STAT3
STIP1
STUB1
SUGT1
SUMO2
SVIL
TBK1
TERT
TJP1
TNFRSF1A
TOMM34
TOMM40
TOMM70
TP53
TTK
TTR
UBASH3A
UBE2N
UCHL1
UNC45A
USP19
USP50
WASL
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Entrez ID |
6613 |
3320 |
HPRD ID |
04332 |
00777 |
Ensembl ID |
ENSG00000188612
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ENSG00000080824
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Uniprot IDs |
A0A024R8S3
P61956
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K9JA46
P07900
Q86SX1
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PDB IDs |
1WM2
1WM3
1WZ0
1Z5Q
2AWT
2CKH
2D07
2IO0
2IO3
2IYD
2N1W
2N9E
2RPQ
3UIN
3UIO
3ZO5
4BKG
4NPN
5D2M
5ELU
5EQL
5GHB
5GHC
6JXW
6JXX
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1BYQ
1OSF
1UY6
1UY7
1UY8
1UY9
1UYC
1UYD
1UYE
1UYF
1UYG
1UYH
1UYI
1UYK
1UYL
1YC1
1YC3
1YC4
1YER
1YES
1YET
2BSM
2BT0
2BUG
2BYH
2BYI
2BZ5
2C2L
2CCS
2CCT
2CCU
2FWY
2FWZ
2H55
2JJC
2K5B
2QF6
2QFO
2QG0
2QG2
2UWD
2VCI
2VCJ
2WI1
2WI2
2WI3
2WI4
2WI5
2WI6
2WI7
2XAB
2XDK
2XDL
2XDS
2XDU
2XDX
2XHR
2XHT
2XHX
2XJG
2XJJ
2XJX
2XK2
2YE2
2YE3
2YE4
2YE5
2YE6
2YE7
2YE8
2YE9
2YEA
2YEB
2YEC
2YED
2YEE
2YEF
2YEG
2YEH
2YEI
2YEJ
2YI0
2YI5
2YI6
2YI7
2YJW
2YJX
2YK2
2YK9
2YKB
2YKC
2YKE
2YKI
2YKJ
3B24
3B25
3B26
3B27
3B28
3BM9
3BMY
3D0B
3EKO
3EKR
3FT5
3FT8
3HEK
3HHU
3HYY
3HYZ
3HZ1
3HZ5
3INW
3INX
3K97
3K98
3K99
3MNR
3O0I
3OW6
3OWB
3OWD
3Q6M
3Q6N
3QDD
3QTF
3R4M
3R4N
3R4O
3R4P
3R91
3R92
3RKZ
3RLP
3RLQ
3RLR
3T0H
3T0Z
3T10
3T1K
3T2S
3TUH
3VHA
3VHC
3VHD
3WHA
3WQ9
4AIF
4AWO
4AWP
4AWQ
4B7P
4BQG
4BQJ
4CGQ
4CGU
4CGV
4CGW
4CWF
4CWN
4CWO
4CWP
4CWQ
4CWR
4CWS
4CWT
4EEH
4EFT
4EFU
4EGH
4EGI
4EGK
4FCP
4FCQ
4FCR
4HY6
4JQL
4L8Z
4L90
4L91
4L93
4L94
4LWE
4LWF
4LWG
4LWH
4LWI
4NH7
4NH8
4O04
4O05
4O07
4O09
4O0B
4R3M
4U93
4W7T
4XIP
4XIQ
4XIR
4XIT
4YKQ
4YKR
4YKT
4YKU
4YKW
4YKX
4YKY
4YKZ
5CF0
5FNC
5FND
5FNF
5GGZ
5J20
5J27
5J2V
5J2X
5J64
5J6L
5J6M
5J6N
5J80
5J82
5J86
5J8M
5J8U
5J9X
5LNY
5LNZ
5LO0
5LO1
5LO5
5LO6
5LQ9
5LR1
5LR7
5LRL
5LRZ
5LS1
5M4E
5M4H
5NYH
5NYI
5OCI
5OD7
5ODX
5T21
5VYY
5XQD
5XQE
5XR5
5XR9
5XRB
5XRD
5XRE
5ZR3
6B99
6B9A
6CEO
6CYG
6CYH
6EI5
6EL5
6ELN
6ELO
6ELP
6EY8
6EY9
6EYA
6EYB
6F1N
6FCJ
6FDP
6GP4
6GP8
6GPF
6GPH
6GPO
6GPP
6GPR
6GPT
6GPW
6GPY
6GQ6
6GQR
6GQS
6GQU
6GR1
6GR3
6GR4
6GR5
6HHR
6KSQ
6N8X
6OLX
6TN4
6TN5
6U98
6U99
6U9A
6U9B
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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