SMS and LARP7

Data Source:
BioGRID (affinity chromatography technology)

		SMS	LARP7
Description		spermine synthase	La ribonucleoprotein 7, transcriptional regulator
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Nucleoplasm Cytosol 7SK SnRNP Ribonucleoprotein Complex
	Molecular Function	Spermine Synthase Activity	RNA Binding Protein Binding U6 SnRNA Binding 7SK SnRNA Binding
	Biological Process	Methionine Metabolic Process Polyamine Metabolic Process Spermine Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Box C/D RNA 3'-end Processing MRNA Processing Spermatogenesis RNA Splicing Cell Differentiation Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II U6 2'-O-snRNA Methylation
Pathways		Metabolism of polyamines
Drugs		Spermine
Diseases		Snyder-Robinson syndrome
GWAS			Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Dental caries (decayed and filled deciduous teeth) ( 31533690) Meat-related diet ( 32066663) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: EZH2 MAPK6 MAPK8IP2 MAPKAPK3 RPS6KA3	76 interacting genes: APP JMJD6 LRRK2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRPF40A RN7SK
Entrez ID		6611	51574
HPRD ID		02115	17095
Ensembl ID		ENSG00000102172	ENSG00000174720
Uniprot IDs		P52788	Q4G0J3
PDB IDs		3C6K 3C6M	4WKR 5KNW 6D12
Enriched GO Terms of Interacting Partners?
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