PLEKHA3 and MORF4L1

Data Source:
BioGRID (two hybrid)

		PLEKHA3	MORF4L1
Description		pleckstrin homology domain containing A3	mortality factor 4 like 1
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Membrane	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Identical Protein Binding Phosphatidylinositol-4-phosphate Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity	Protein Binding Protein N-terminus Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Biological_process Ceramide Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways		Synthesis of PIPs at the plasma membrane	HATs acetylate histones
Drugs
Diseases
GWAS		Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)	Coronary artery disease ( 32469254 30104761 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		8 interacting genes: DOK3 ERRFI1 MORF4L1 MRPL45 MYO15B RNMT SH2B2 TCL1B	76 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 CALM1 CAMK2B CEP57L1 CWC27 DMAP1 DRAP1 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TULP3 UBP1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449
Entrez ID		65977	10933
HPRD ID		09688	09532
Ensembl ID		ENSG00000116095	ENSG00000185787
Uniprot IDs		Q9HB20	Q9UBU8
PDB IDs		2KCJ 2MDX 3RCP	2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE
Enriched GO Terms of Interacting Partners?
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