SLC10A2 and UPK1B

Data Source:
BioGRID (two hybrid)

		SLC10A2	UPK1B
Description		solute carrier family 10 member 2	uroplakin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane	Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity	Structural Molecule Activity Protein Binding
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport	Response To Bacterium Epithelial Cell Differentiation
Pathways		Recycling of bile acids and salts
Drugs		Volixibat
Diseases		Primary bile acid malabsorption
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) epithelial cell adhesion molecule levels ( 25147954) Esophageal cancer (alcohol interaction) ( 22960999) Gallstone disease ( 30504769) Late-onset Alzheimer's disease ( 27770636) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Response to quetiapine in schizophrenia ( 29503163) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
Interacting Genes		10 interacting genes: C3orf52 CCL4L2 CTXN3 EFNA5 IFITM3 NRM PSENEN TEX264 TMEM222 UPK1B	53 interacting genes: BCL2L13 BEST2 BNIP2 CD53 CD69 CERS4 CLDN7 DAGLA EDAR FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A2 SLC16A2 SLC35C2 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM262 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1
Entrez ID		6555	7348
HPRD ID		03189	03853
Ensembl ID		ENSG00000125255	ENSG00000114638
Uniprot IDs		Q12908	O75841
PDB IDs
Enriched GO Terms of Interacting Partners?
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