LGALS7B and YAF2

Data Source:
BioGRID (two hybrid)

		LGALS7B	YAF2
Description		galectin 7B	YY1 associated factor 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Extracellular Exosome	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Galactoside Binding Carbohydrate Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Gene Expression Negative Regulation Of Interferon-gamma Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs		Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Refractive error ( 32231278)
Interacting Genes		6 interacting genes: HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2	29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		653499	10138
HPRD ID		19145	09606
Ensembl ID		ENSG00000178934	ENSG00000015153
Uniprot IDs		P47929	B4DJQ9 G3V212 Q8IY57
PDB IDs		1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S	2D9G
Enriched GO Terms of Interacting Partners?
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