FAM228A and GYS1

Data Source:
BioGRID (two hybrid)

		FAM228A	GYS1
Description		family with sequence similarity 228 member A	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process		Glycogen Biosynthetic Process Heart Development
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		White blood cell count ( 32888494)
Interacting Genes		18 interacting genes: BYSL CCDC57 CDKN2D COX5B EAF1 ENKD1 FAM90A1 GYS1 HSF2BP LMO2 LMO4 MLH1 PLEKHA7 SAT1 SCNM1 SPANXN3 TNS2 ZNF76	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		653140	2997
HPRD ID		19048	00721
Ensembl ID		ENSG00000186453	ENSG00000104812
Uniprot IDs		Q86W67	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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