MRPL11 and VPS52

Data Source:
BioGRID (two hybrid)

		MRPL11	VPS52
Description		mitochondrial ribosomal protein L11	VPS52 subunit of GARP complex
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding	Protein Binding Syntaxin Binding
	Biological Process	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Low density lipoprotein cholesterol levels ( 32154731)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		32 interacting genes: AGTRAP APP CAMK2A CAMK2B CAMK2D CAMK2G CCDC172 CRYAB ERCC6 FSD2 GOLGA6L9 HMBOX1 HOMEZ JAKMIP1 JAKMIP2 KRT40 MRPL54 MTUS2 PDCL PNMA1 SLC16A9 STX2 TAX1BP1 TFCP2 TFIP11 THAP1 VPS52 ZBTB14 ZBTB2 ZBTB8A ZNF438 ZNF526	104 interacting genes: AAMP ARNT2 ATP6V1D BORCS6 BYSL C1orf109 C1orf216 C2CD6 CABP5 CACNA1A CCDC102B CCDC13 CCDC146 CCDC185 CCDC187 CCDC33 CCDC57 CCHCR1 CDC20B CDC5L CDK18 CEP19 CFAP206 CWF19L2 DCX DDX6 DNAJC11 DTNB EEF1AKNMT EPM2AIP1 FAM110A FAM161A FAM161B FAM184A FAM50B GEM GFM2 GOLGA1 GORASP2 GPKOW HAUS1 HDAC4 HEATR1 HGS HOXB5 JAKMIP2 KANK2 KIAA1217 KIF5B KIF9 KIFC3 KLC3 KLHL42 LMO4 LNX1 MAGEL2 MAPK3 MFAP1 MRPL1 MRPL11 NDC80 NFKBIB NOP2 NR2C2AP OTUD6A PIMREG PKN3 PPP1R18 PRKAA1 PRKAA2 RAB4A RAB4B RABEP2 RNF41 RUNX1T1 SCNM1 SH2D4A SMARCE1 STX11 TAB2 TBC1D1 TBC1D22B TCEANC TCP11L1 TEAD4 THAP11 TPM3 TRAF4 TRAF6 TSSK3 TSTD2 TXLNA TXLNB TXN2 USP2 VEZF1 VPS28 VPS53 WASHC3 WTAP ZC2HC1C ZMAT2 ZNF417 ZNF587
Entrez ID		65003	6293
HPRD ID		14739	09142
Ensembl ID		ENSG00000174547	ENSG00000223501
Uniprot IDs		Q9Y3B7	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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