BMP1 and CST7

Data Source:
BioGRID (biochemical)

		BMP1	CST7
Description		bone morphogenetic protein 1	cystatin F
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Vesicle	Extracellular Space Lysosome Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Golgi Apparatus Cytoplasmic Vesicle
	Molecular Function	Metalloendopeptidase Activity Cytokine Activity Calcium Ion Binding Protein Binding Growth Factor Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Identical Protein Binding	Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	Skeletal System Development Cartilage Condensation Ossification Proteolysis Signal Transduction Multicellular Organism Development Extracellular Matrix Disassembly Cell Differentiation High-density Lipoprotein Particle Assembly Positive Regulation Of Cartilage Development	Immune Response Negative Regulation Of Peptidase Activity Positive Regulation Of Myelination Inhibition Of Cysteine-type Endopeptidase Activity Negative Regulation Of Microglial Cell Activation
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323) Waist-to-hip ratio adjusted for BMI ( 28552196)	Alcohol consumption (drinks per week) ( 30643258) Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		14 interacting genes: ADRA1A CHRD COL1A1 COL5A1 COL5A2 COL7A1 GEM HSPG2 LAMA3 LAMB3 LAMC2 TP53 TWSG1 YLPM1	2 interacting genes: CTSB CTSL
Entrez ID		649	8530
HPRD ID		00209	04458
Ensembl ID		ENSG00000168487	ENSG00000077984
Uniprot IDs		P13497	O76096
PDB IDs		3EDG 3EDH 6BSL 6BSM 6BTN 6BTO 6BTP 6BTQ	2CH9
Enriched GO Terms of Interacting Partners?
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