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BMP1

Description bone morphogenetic protein 1
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Golgi Apparatus
  • Vesicle
Molecular Function
  • Metalloendopeptidase Activity
  • Cytokine Activity
  • Calcium Ion Binding
  • Protein Binding
  • Growth Factor Activity
  • Peptidase Activity
  • Metallopeptidase Activity
  • Zinc Ion Binding
  • Identical Protein Binding
Biological Process
  • Skeletal System Development
  • Cartilage Condensation
  • Ossification
  • Proteolysis
  • Signal Transduction
  • Multicellular Organism Development
  • Extracellular Matrix Disassembly
  • Cell Differentiation
  • High-density Lipoprotein Particle Assembly
  • Positive Regulation Of Cartilage Development
Pathways
  • Degradation of the extracellular matrix
  • Degradation of the extracellular matrix
  • Collagen biosynthesis and modifying enzymes
  • Anchoring fibril formation
  • Crosslinking of collagen fibrils
Drugs
Diseases
GWAS
  • Coronary artery disease ( 29212778)
  • Hypertriglyceridemia ( 23505323)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Novel Interacting Genes 4 novel interacting genes: CLIP2 CST7 DST PTPRZ1
Interacting Genes 14 interacting genes: ADRA1A CHRD COL1A1 COL5A1 COL5A2 COL7A1 GEM HSPG2 LAMA3 LAMB3 LAMC2 TP53 TWSG1 YLPM1
Entrez ID 649
HPRD ID 00209
Ensembl ID ENSG00000168487
Uniprot IDs P13497
PDB IDs 3EDG 3EDH 6BSL 6BSM 6BTN 6BTO 6BTP 6BTQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025