SHOX and IGBP1

Data Source:
BioGRID (two hybrid)

		SHOX	IGBP1
Description		short stature homeobox	immunoglobulin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Regulation Of Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Microtubule-based Movement Response To Interleukin-1
Pathways
Drugs
Diseases		SHOX-related haploinsufficiency disorders, including: Isolated short stature; Langer syndrome; Leri-Weill syndrome	Corpus callosum, agenesis of, with mental retardation, ocular coloboma and micrognathia
GWAS
Interacting Genes		5 interacting genes: CSNK2A1 GLIS2 HEMK1 IGBP1 NKX2-5	12 interacting genes: APP HSPB1 LINC01257 MID1 MID2 PPP2CA PPP4C PPP6C PYGM REXO5 S100A13 SHOX
Entrez ID		6473	3476
HPRD ID		02430	02140
Ensembl ID		ENSG00000185960	ENSG00000089289
Uniprot IDs		A0A024R385 O15266	P78318
PDB IDs			4IYP
Enriched GO Terms of Interacting Partners?
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