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SHOX

Description short stature homeobox
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • Protein Binding
  • Sequence-specific DNA Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Skeletal System Development
  • Regulation Of Transcription By RNA Polymerase II
  • Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
  • SHOX-related haploinsufficiency disorders, including: Isolated short stature; Langer syndrome; Leri-Weill syndrome
GWAS
Interacting Genes 5 interacting genes: CSNK2A1 GLIS2 HEMK1 IGBP1 NKX2-5
Entrez ID 6473
HPRD ID 02430
Ensembl ID ENSG00000185960
Uniprot IDs A0A024R385 O15266
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025