CEP170P1 and CENPO

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		CEP170P1	CENPO
Description		centrosomal protein 170 pseudogene 1	centromere protein O
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process		CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 25760438)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)
Interacting Genes		18 interacting genes: ABI3 ARHGDIG C19orf25 C1orf216 CCDC120 CCDC146 CENPO CLHC1 HAUS1 KXD1 LMO1 LMO3 LMO4 OIP5 RALYL RUNX1T1 SMARCE1 SSC5D	7 interacting genes: CENPP CEP170P1 DCDC2 ERI3 FOS FOSB NECAB2
Entrez ID		645455	79172
HPRD ID			14414
Ensembl ID			ENSG00000138092
Uniprot IDs			Q9BU64
PDB IDs
Enriched GO Terms of Interacting Partners?
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