MRPS25 and NUAK1

Data Source:
BioGRID (affinity chromatography technology)

		MRPS25	NUAK1
Description		mitochondrial ribosomal protein S25	NUAK family kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Ribosome	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Structural Constituent Of Ribosome	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Mitochondrial Translational Elongation Mitochondrial Translational Termination	Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Cell Adhesion Regulation Of Myosin-light-chain-phosphatase Activity Intracellular Signal Transduction Regulation Of Cell Population Proliferation Cellular Response To Glucose Starvation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Regulation of TP53 Activity through Phosphorylation
Drugs			Fostamatinib
Diseases
GWAS			Alzheimer's disease biomarkers ( 23419831) Attention function in attention deficit hyperactive disorder ( 26174813) Brain morphology (MOSTest) ( 32665545) General glucose level in pregnancy (gestational week 30-32) ( 30324795) Lateral ventricular volume in normal aging ( 30258056) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Two-hour glucose in pregnancy (gestational week 30-32) ( 30324795)
Interacting Genes		1 interacting genes: ERCC6	5 interacting genes: APP CASP6 FBXO25 LATS1 PPP1CC
Entrez ID		64432	9891
HPRD ID		17594	12171
Ensembl ID		ENSG00000131368	ENSG00000074590
Uniprot IDs		P82663	A0A024RBL3 O60285
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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