SGCA and SGCB

Data Source:
HPRD (in vivo)

		SGCA	SGCB
Description		sarcoglycan alpha	sarcoglycan beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cell-cell Junction Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcolemma Membrane Raft	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	Muscle Contraction Muscle Organ Development Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Tissue Regeneration	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development
Pathways
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)	Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Heel bone mineral density ( 30598549) Temporomandibular joint disorder ( 28081371) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		8 interacting genes: FN1 FSTL1 ITGB1BP2 SGCB SGCD SGTA SGTB TAF1	22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63
Entrez ID		6442	6443
HPRD ID		02525	02942
Ensembl ID		ENSG00000108823	ENSG00000163069
Uniprot IDs		A0A0S2Z4P8 A0A0S2Z4Q1 Q16586	Q16585 Q5U0N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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