SGCB and ADAM33

Data Source:
BioGRID (two hybrid)

		SGCB	ADAM33
Description		sarcoglycan beta	ADAM metallopeptidase domain 33
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma	Integral Component Of Membrane
	Molecular Function	Protein Binding	Metalloendopeptidase Activity Zinc Ion Binding
	Biological Process	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development	Proteolysis
Pathways
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)	Asthma
GWAS			Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63	33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21
Entrez ID		6443	80332
HPRD ID		02942	06173
Ensembl ID		ENSG00000163069	ENSG00000149451
Uniprot IDs		Q16585 Q5U0N0	A2A2L3 Q9BZ11
PDB IDs			1R54 1R55
Enriched GO Terms of Interacting Partners?
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