CENPK and AP1G2

Data Source:
BioGRID (two hybrid)

		CENPK	AP1G2
Description		centromere protein K	adaptor related protein complex 1 subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Inner Kinetochore Nucleoplasm Cytosol	Golgi Membrane Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane AP-1 Adaptor Complex Transport Vesicle
	Molecular Function	Protein Binding	Protein Binding Clathrin Adaptor Activity Cargo Adaptor Activity
	Biological Process	Mitotic Sister Chromatid Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Viral Process Vesicle-mediated Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 30072576) Sudden cardiac arrest ( 21658281)
Interacting Genes		11 interacting genes: AP1G2 CENPH HSPB1 MRFAP1L1 PCBD2 PEX14 RTN4IP1 SOX6 TRIM55 TRIM63 WASHC3	13 interacting genes: AAGAB AFTPH AP1B1 AP1S1 AP1S2 ATXN1L CENPK KDM1A NEDD4 PRMT6 RABEP1 SYNRG XRN1
Entrez ID		64105	8906
HPRD ID		13323	04638
Ensembl ID		ENSG00000123219	ENSG00000213983
Uniprot IDs		D6RHD3 Q9BS16	O75843 Q86U03 Q86V28
PDB IDs			2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?
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