ELSPBP1 and TAL1

Data Source:
HPRD (in vivo, two hybrid)

		ELSPBP1	TAL1
Description		epididymal sperm binding protein 1	TAL bHLH transcription factor 1, erythroid differentiation factor
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Lsd1/2 Complex
	Molecular Function	Heparin Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Protein Dimerization Activity E-box Binding
	Biological Process	Single Fertilization Sperm Capacitation	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Locomotory Behavior Spinal Cord Association Neuron Differentiation Hemopoiesis Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Positive Regulation Of Protein-containing Complex Assembly Embryonic Hemopoiesis Megakaryocyte Development Regulation Of Cell Population Proliferation Erythrocyte Maturation Cell Fate Commitment Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Division Astrocyte Fate Commitment Definitive Hemopoiesis Hemangioblast Cell Differentiation Hematopoietic Stem Cell Differentiation Regulation Of Mast Cell Differentiation Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Stem Cell Population Maintenance Positive Regulation Of Signaling Receptor Activity
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs Transcriptional regulation of granulopoiesis
Drugs		N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Intelligence ( 22449649) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Refractive error ( 32231278)	Adult body size ( 32376654) Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		4 interacting genes: MYOD1 NEDD9 PSMD9 TAL1	23 interacting genes: CHD3 DRG1 ELSPBP1 EP300 GATA1 GATA2 GATA3 HDAC1 HOXB9 KAT2B KDM1A LMO1 LMO2 MAPK3 NCAPG2 PRKCQ SIN3A SKP2 SP1 STUB1 TCF3 TCF4 ZHX1
Entrez ID		64100	6886
HPRD ID		12119	01753
Ensembl ID		ENSG00000169393	ENSG00000162367
Uniprot IDs		A0A384NKL6 Q96BH3	P17542 Q16509
PDB IDs			2YPA 2YPB
Enriched GO Terms of Interacting Partners?
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