TAL1

Description		TAL bHLH transcription factor 1, erythroid differentiation factor
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GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Lsd1/2 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Protein Dimerization Activity E-box Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Locomotory Behavior Spinal Cord Association Neuron Differentiation Hemopoiesis Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Positive Regulation Of Protein-containing Complex Assembly Embryonic Hemopoiesis Megakaryocyte Development Regulation Of Cell Population Proliferation Erythrocyte Maturation Cell Fate Commitment Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Division Astrocyte Fate Commitment Definitive Hemopoiesis Hemangioblast Cell Differentiation Hematopoietic Stem Cell Differentiation Regulation Of Mast Cell Differentiation Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Stem Cell Population Maintenance Positive Regulation Of Signaling Receptor Activity
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Transcriptional regulation of granulopoiesis
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Adult body size ( 32376654) Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)
Novel Interacting Genes		1 novel interacting genes: STOML2
Interacting Genes		23 interacting genes: CHD3 DRG1 ELSPBP1 EP300 GATA1 GATA2 GATA3 HDAC1 HOXB9 KAT2B KDM1A LMO1 LMO2 MAPK3 NCAPG2 PRKCQ SIN3A SKP2 SP1 STUB1 TCF3 TCF4 ZHX1
Entrez ID		6886
HPRD ID		01753
Ensembl ID		ENSG00000162367
Uniprot IDs		P17542 Q16509
PDB IDs		2YPA 2YPB
Enriched GO Terms of Interacting Partners?
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