SAMSN1 and SAP30

		SAMSN1	SAP30
Description		SAM domain, SH3 domain and nuclear localization signals 1	Sin3A associated protein 30
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GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	Phosphotyrosine Residue Binding RNA Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Skeletal Muscle Cell Differentiation
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
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Diseases
GWAS		Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		64092	8819
HPRD ID		06413	04540
Ensembl ID		ENSG00000155307	ENSG00000164105
Uniprot IDs		Q9NSI8 S6FRS6	O75446
PDB IDs		6UZJ	2KDP
Enriched GO Terms of Interacting Partners?
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