PBLD and STRAP

Data Source:
HPRD (two hybrid)

		PBLD	STRAP
Description		phenazine biosynthesis like protein domain containing	serine/threonine kinase receptor associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex
	Molecular Function	Molecular_function Protein Binding Isomerase Activity Identical Protein Binding	RNA Binding Signaling Receptor Binding Protein Binding
	Biological Process	Biosynthetic Process Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal SnRNP Assembly Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathways			Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS		Optic disc parameters ( 20548946) Optic disc radius ( 31597446) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Optic nerve measurement (disc area) ( 20395239) Vertical cup-disc ratio ( 20548946)
Interacting Genes		11 interacting genes: AMOT BEND7 CCDC184 EFHC2 GRAP2 LNX1 STRAP TCF4 TRIP13 VAC14 ZRANB1	27 interacting genes: CHEK2 GEMIN6 GEMIN7 MAP1B MTRES1 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2
Entrez ID		64081	11171
HPRD ID		14366	05816
Ensembl ID		ENSG00000108187	ENSG00000023734
Uniprot IDs		A0A024QZK5 P30039	B0AZV0 Q9Y3F4
PDB IDs
Enriched GO Terms of Interacting Partners?
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