SELL and PODXL

Data Source:
HPRD (in vivo)

		SELL	PODXL
Description		selectin L	podocalyxin like
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane	Ruffle Extracellular Space Nucleolus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Microvillus Membrane Centriolar Satellite Slit Diaphragm Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome
	Molecular Function	Protease Binding Calcium Ion Binding Protein Binding Heparin Binding Carbohydrate Binding Glycosphingolipid Binding Oligosaccharide Binding	Protein Binding
	Biological Process	Cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Degranulation Regulation Of Immune Response Leukocyte Migration Leukocyte Tethering Or Rolling	Cell Adhesion Negative Regulation Of Cell Adhesion Cell Migration Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Migration Regulation Of Microvillus Assembly Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Glomerular Visceral Epithelial Cell Development Epithelial Tube Formation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Acne (severe) ( 24399259) Amyotrophic lateral sclerosis ( 19451621) Basophil percentage of white cells ( 32888494) Blood protein levels ( 30072576 29875488 28240269) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479)	Alcohol dependence symptom count ( 27151647) Diastolic blood pressure ( 27841878) Hypertension ( 28273873) Idiopathic dilated cardiomyopathy ( 29495422) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 30578418) Schizophrenia ( 25056061) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		16 interacting genes: CD4 CFH EMCN EZR GRB2 MSN MUC7 PODXL PODXL2 PRKCA PRKCQ PRKG1 SELE SELPLG SLC30A2 VCAN	4 interacting genes: SELL SGTB SLC9A3R2 UBQLN2
Entrez ID		6402	5420
HPRD ID		07034	04025
Ensembl ID		ENSG00000188404	ENSG00000128567
Uniprot IDs		P14151	O00592 Q96N83
PDB IDs		1KJB 2LGF 3CFW 5VC1
Enriched GO Terms of Interacting Partners?
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