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CCL19 and DCTN3
Data Source:
HPRD
(in vivo)
CCL19
DCTN3
Description
C-C motif chemokine ligand 19
dynactin subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Condensed Chromosome Kinetochore
Nucleolus
Centrosome
Spindle
Cytosol
Dynactin Complex
Microtubule
Midbody
Cleavage Furrow
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Chemokine Activity
CCR7 Chemokine Receptor Binding
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Structural Molecule Activity
Protein Binding
Biological Process
Establishment Of T Cell Polarity
Immunological Synapse Formation
Dendritic Cell Chemotaxis
Myeloid Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Cellular Calcium Ion Homeostasis
Inflammatory Response
Immune Response
Cell Communication
G Protein-coupled Receptor Signaling Pathway
Activation Of JUN Kinase Activity
Response To Virus
Positive Regulation Of Glycoprotein Biosynthetic Process
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
T Cell Costimulation
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Tumor Necrosis Factor Production
Response To Prostaglandin E
Positive Regulation Of T Cell Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Lymphocyte Chemotaxis
Positive Regulation Of Receptor-mediated Endocytosis
Cell Maturation
Positive Regulation Of Chemotaxis
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Protein Kinase B Signaling
Regulation Of Cell Projection Assembly
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Response To Nitric Oxide
Positive Regulation Of Neutrophil Chemotaxis
Mature Conventional Dendritic Cell Differentiation
Cellular Response To Virus
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Cell Motility
Positive Regulation Of Dendritic Cell Dendrite Assembly
Negative Regulation Of Dendritic Cell Apoptotic Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cytoskeleton-dependent Cytokinesis
Ciliary Basal Body-plasma Membrane Docking
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
MHC class II antigen presentation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
8 interacting genes:
ACKR2
ACKR4
CCL22
CCR10
CCR7
CXCL13
MEOX2
PF4V1
11 interacting genes:
ATXN1
DCTN1
GSK3B
KRT34
NUP54
PBX2
PITX1
TRIM55
TRIP13
USHBP1
VPS37C
Entrez ID
6363
11258
HPRD ID
03750
06303
Ensembl ID
ENSG00000172724
ENSG00000137100
Uniprot IDs
Q6IBD6
Q99731
O75935
X6RLR1
PDB IDs
2MP1
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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