CCL14 and CCL22

Data Source:
BioGRID (pull down)

		CCL14	CCL22
Description		C-C motif chemokine ligand 14	C-C motif chemokine ligand 22
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Cellular Calcium Ion Homeostasis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways			Chemokine receptors bind chemokines Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Metabolite levels ( 23823483) Upper eyelid sagging severity ( 24869959)	Asthma ( 32296059) Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 24076602) Systemic lupus erythematosus ( 28714469)
Interacting Genes		9 interacting genes: ACKR2 AKT2 CCL11 CCL22 CCR1 CCR3 CCR5 DDX39A PIK3R1	10 interacting genes: AQP6 CCL14 CCL19 CCR4 CRYAB DPP4 GCLC HERC3 PF4V1 VCAM1
Entrez ID		6358	6367
HPRD ID		03231	04263
Ensembl ID		ENSG00000276409	ENSG00000102962
Uniprot IDs		Q16627	O00626
PDB IDs		2Q8R 2Q8T
Enriched GO Terms of Interacting Partners?
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