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CCL13 and CXCL10
Data Source:
BioGRID
(pull down, pull down)
CCL13
CXCL10
Description
C-C motif chemokine ligand 13
C-X-C motif chemokine ligand 10
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Molecular Function
Signaling Receptor Binding
Protein Binding
Chemokine Activity
CCR Chemokine Receptor Binding
Signaling Receptor Binding
Protein Binding
Chemokine Activity
Heparin Binding
CAMP-dependent Protein Kinase Regulator Activity
Chemoattractant Activity
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Biological Process
Monocyte Chemotaxis
Cellular Calcium Ion Homeostasis
Chemotaxis
Inflammatory Response
Cytoskeleton Organization
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Regulation Of Cell Shape
Neutrophil Chemotaxis
Killing Of Cells Of Other Organism
Positive Regulation Of GTPase Activity
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Chemotaxis
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Muscle Organ Development
Blood Circulation
Positive Regulation Of Cell Population Proliferation
Response To Cold
Response To Gamma Radiation
T Cell Chemotaxis
Regulation Of T Cell Chemotaxis
Response To Auditory Stimulus
Negative Regulation Of Angiogenesis
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
Response To Vitamin D
Cellular Response To Heat
Endothelial Cell Activation
Regulation Of Cell Population Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Myoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Chemotaxis
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Positive Regulation Of Monocyte Chemotaxis
Regulation Of Endothelial Tube Morphogenesis
Negative Regulation Of Myoblast Fusion
Positive Regulation Of T Cell Migration
Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Drugs
N-Methylleucine
Eldelumab
Clove oil
Diseases
GWAS
Blood protein levels (
29875488
)
Crohn's disease (
22412388
)
Inflammatory bowel disease (
23128233
)
Metabolite levels (
23823483
)
Blood protein levels (
30072576
29875488
28240269
)
C-X-C motif chemokine 10 levels (
25147954
)
Hippocampal volume (
29274321
)
Interferon gamma-induced protein 10 levels (
27989323
31217265
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Interacting Genes
26 interacting genes:
ACKR2
ACKR4
APP
CCL11
CCL2
CCL21
CCL24
CCL26
CCL28
CCL5
CCL8
CCR3
CCR5
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL9
HNRNPH3
MMP1
MMP3
NOD2
PF4
PPBP
XCL1
22 interacting genes:
CCL11
CCL13
CCL21
CCL26
CCL28
CCL5
CCL8
CCR3
CXCL11
CXCL12
CXCL14
CXCL17
CXCL6
CXCL9
CXCR3
DPP4
IGFBP7
PF4
PF4V1
PPBP
VCAN
XCL1
Entrez ID
6357
3627
HPRD ID
03230
00930
Ensembl ID
ENSG00000181374
ENSG00000169245
Uniprot IDs
Q99616
P02778
PDB IDs
2RA4
1LV9
1O7Y
1O7Z
1O80
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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