CCL8 and SDF2

Data Source:
HPRD (in vivo)

		CCL8	SDF2
Description		C-C motif chemokine ligand 8	stromal cell derived factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Endoplasmic Reticulum Membrane Chaperone Complex
	Molecular Function	Protein Kinase Activity Protein Binding Chemokine Activity Heparin Binding Phospholipase Activator Activity CCR Chemokine Receptor Binding	Misfolded Protein Binding
	Biological Process	Monocyte Chemotaxis Positive Regulation Of Leukocyte Migration Protein Phosphorylation Calcium Ion Transport Cellular Calcium Ion Homeostasis Exocytosis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Genome Replication Eosinophil Chemotaxis Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Leukocyte Proliferation Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Chaperone Cofactor-dependent Protein Refolding
Pathways
Drugs		Pidolic acid	Malonate Ion
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Crohn's disease ( 22412388)
Interacting Genes		20 interacting genes: ACKR1 ACKR2 ACKR4 CCL11 CCL13 CCL2 CCL26 CCR1 CCR3 CCR5 CXCL10 CXCL11 CXCL17 CXCL2 CXCL6 CXCL8 MMP3 PPBP VCAN XCL2	3 interacting genes: HNRNPD HSPB2 UBC
Entrez ID		6355	6388
HPRD ID		03791	04243
Ensembl ID		ENSG00000108700	ENSG00000132581
Uniprot IDs		P80075	Q6IBU4 Q99470
PDB IDs		1ESR
Enriched GO Terms of Interacting Partners?
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