SCN4B and SC5D

Data Source:
BioGRID (pull down)

		SCN4B	SC5D
Description		sodium voltage-gated channel beta subunit 4	sterol-C5-desaturase
Image			No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Intercalated Disc Intrinsic Component Of Plasma Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Sodium Channel Regulator Activity Ion Channel Binding Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity
	Biological Process	Sodium Ion Transport Positive Regulation Of Sodium Ion Transport Sodium Ion Transmembrane Transport Cardiac Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Cardiac Muscle Cell Action Potential AV Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Lipid Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Regulation Of Cholesterol Biosynthetic Process
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation	Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs		Ranolazine Valproic acid Oxcarbazepine Cocaine Zonisamide Brivaracetam Dichlorobenzyl alcohol Fish oil
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Interacting Genes		2 interacting genes: SCN2A YIF1A
Entrez ID		6330	6309
HPRD ID		09749	09078
Ensembl ID		ENSG00000177098	ENSG00000109929
Uniprot IDs		B0YJ93 Q8IWT1	A0A024R3G4 O75845
PDB IDs		4MZ2 4MZ3 5XAW 6VSV
Enriched GO Terms of Interacting Partners?
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