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SCN4B

Description sodium voltage-gated channel beta subunit 4
Image
GO Annotations Cellular Component
  • Voltage-gated Sodium Channel Complex
  • Intercalated Disc
  • Intrinsic Component Of Plasma Membrane
Molecular Function
  • Voltage-gated Ion Channel Activity
  • Voltage-gated Sodium Channel Activity
  • Protein Binding
  • Sodium Channel Regulator Activity
  • Ion Channel Binding
  • Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential
Biological Process
  • Sodium Ion Transport
  • Positive Regulation Of Sodium Ion Transport
  • Sodium Ion Transmembrane Transport
  • Cardiac Muscle Contraction
  • Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
  • Cardiac Muscle Cell Action Potential Involved In Contraction
  • Membrane Depolarization During Cardiac Muscle Cell Action Potential
  • AV Node Cell Action Potential
  • Regulation Of Heart Rate By Cardiac Conduction
  • Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
  • Interaction between L1 and Ankyrins
  • Phase 0 - rapid depolarisation
Drugs
  • Ranolazine
  • Valproic acid
  • Oxcarbazepine
  • Cocaine
  • Zonisamide
  • Brivaracetam
  • Dichlorobenzyl alcohol
  • Fish oil
Diseases
  • Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Novel Interacting Genes 1 novel interacting genes: SC5D
Interacting Genes 2 interacting genes: SCN2A YIF1A
Entrez ID 6330
HPRD ID 09749
Ensembl ID ENSG00000177098
Uniprot IDs B0YJ93 Q8IWT1
PDB IDs 4MZ2 4MZ3 5XAW 6VSV
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025