SAT1 and HOXB6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAT1	HOXB6
Description		spermidine/spermine N1-acetyltransferase 1	homeobox B6
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Chromatin Nucleus
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis
Pathways		Interconversion of polyamines
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS			Childhood body mass index ( 26604143) Hemoglobin ( 32888494)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TEAD4 TEX43 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	17 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 GYS1 HOXB7 KRT15 NEK6 NTAQ1 PKNOX1 PLSCR1 SAT1 SRPK2 TCEAL1 TCF21 TEKT5
Entrez ID		6303	3216
HPRD ID		02431	00849
Ensembl ID		ENSG00000130066	ENSG00000108511
Uniprot IDs		A0A384NQ10 P21673	P17509
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?
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